ABSTRACT
To determine the prevalence of Asherman's syndrome in the south of Iran and assess the safety and efficacy of hysteroscopic adhesiolysis in restoration of menstrual function and fertility, a prospective study was done from 1997 to 1999. Among 2300 couples with infertility referring to the infertility clinic of a Shiraz University hospital, 30 patients were proven to have Asherman's syndrome by diagnostic hysterosalpingography [HSG] and then hysteroscopy. The prevalence of this syndrome was 1.3%. Hysteroscopic adhesiolysis was performed in all 30 patients. Adhesion reformation postoperatively was absent in stage 1 patients, 15% in stage II and 66% in stage III. Normal menstrual flow was restored in all patients [100%], and 19 patients [63.3%] conceived after surgery that resulted in term infants in 15 patients [50%]. Hysteroscopic adhesiolysis is a safe and effective operation for restoring the normal menstrual pattern and fertility, and the severity of the adhesions appear to correlate best with the reproductive outcome